個人簡歷

教育簡歷

• 1994.09-2001.06    東北林業大學                        本科🎊、碩士

• 2001.09-2004.06    沐鸣2平台                            博士生

工作簡歷

• 2004.09-2006.06    上海中醫藥大學                      博士後

• 2006.07-2008.08    沐鸣2平台                            講師

• 2008.09-2009.09    Florida Atlantic University         Postdoctor

• 2009.10-2014.01    沐鸣2平台                            講師

• 2014.01-至今       沐鸣2平台                            副教授,碩導,博導

博士生導師/方向

• 環境健康♌️、基於微流控的生物分析

碩士生導師/方向

• 環境健康、基於微流控的生物分析

學術兼職

• 中國毒理學會會員

人才培養

本科生課程：

• 《環境生物學》

研究生課程：

• 《環境生態學》

科學研究

主持和參與的主要項目：

• 國家自然基金地區科學基金項目💆🏿‍♀️，21966027，基於3D血睾微流控芯片的納米二氧化鈦生殖毒性分子機製研究，2020/01-2023/12🥄🔈，41萬元🏄，在研📍🫷🏼，合作主持

• 國家自然基金面上項目，21876031，應用多器官微流控芯片系統對致癌細顆粒物體內代謝機製的模擬研究🫠，2019/01- 2022/12，77.6 萬元，在研👨‍🎓，主持

• 國家自然基金面上項目，21577020，基於轉錄組測序及微流控芯片技術的PM2.5誘導人細胞促癌信號通路分子機製研究👩🏼‍🦰，2016/01-2019/12💅，77.8萬元🆓🧑🏻‍💻，結題🪝，主持

• 國家自然基金面上項目🎚，21377027，PM2.5對微流控芯片模擬人呼吸及心血管系統的細胞毒性機製研究，2014/01-2017/12👩‍👦，82萬元，結題，主持

• 國家自然基金青年項目，20907010💅，藻毒素降解關鍵酶的高通量篩選及降解機理研究💂🏽‍♂️，2010/01-2012/12，20萬元，結題，主持

教研成果

代表性專著🙌：

代表性論文：

• Lulu Zheng﹟, Yuwen Wang﹟, Yule Zhang, Yongfeng Fu, Zhijin Yang, Yan Fan, Zhen Sun, Mantong Zhao, Lijun Zhu, Bo Dai, Dong An, Dawei Zhang*, Sixiu Liu*, EGFR inhibitors regulate Ca2+ concentration and apoptosis after PM2.5 exposure based on a lung-mimic microfluidic system, Science of the Total Environment, 2020, 761: 143200.

• Xiaoxiao Duan﹟, Lulu Zheng﹟, Xinlian Zhang, Bo Wang, Mingming Xiao, Wang Zhao, Sixiu Liu*, Guodong Sui*, A Membrane-free Liver-Gut-on-Chip Platform for the Assessment on Dysregulated Mechanisms of Cholesterol and Bile Acid Metabolism Induced by PM2.5, ACS Sensors, 2020, 5: 3483-3492.

• Yuhan Yao, Xi Chen, Xinlian Zhang, Qi Liu, Jinhui Zhu, Wang Zhao, Sixiu Liu*, Guodong Sui*, Rapid Detection of Influenza Virus Subtypes Based on an Integrated Centrifugal Disc, ACS Sensors, 2020, 5: 1354-1362.

• Chunmei Ling, Hongmei An, Li Li, Jiaqi Wang, Tianjiao Lu, Haixia Wang, Yunhua Hu, Guanling Song*, and Sixiu Liu*, Genotoxicity Evaluation of Titanium Dioxide Nanoparticles In Vitro: a Systematic Review of the Literature and Meta-analysis, Biological Trace Element Research, 2020, https://doi.org/10.1007/s12011-020-02311-8.

• Lulu Zheng﹟, Heng Dong﹟, Wang Zhao, Xinlian Zhang, Xiaoxiao Duan, Hao Zhang, Sixiu Liu*, Guodong Sui*, An Air–Liquid Interface Organ-Level Lung Microfluidics Platform for Analysis on Molecular Mechanisms of Cytotoxicity Induced by Cancer-Causing Fine Particles, ACS Sensors, 2019, 4(4): 907-917.

• Heng Dong﹟, Lulu Zheng﹟, Xiaoxiao Duan, Wang Zhao, Jianmin Chen, Sixiu Liu*, Guodong Sui*, Cytotoxicity analysis of ambient fine particle in BEAS-2B cells on an air-liquid interface (ALI) microfluidics system, Science of The Total Environment, 2019, 677: 108-119.

• Xiaoxiao Duan﹟, Linlin Zhao﹟, Heng Dong﹟, Wang Zhao, Sixiu Liu*, Guodong Sui*, Microfluidic Immunoassay System for Rapid Detection and Semi-Quantitative Determination of a Potential Serum Biomarker Mesothelin, ACS Sensors, 2019, 4(11): 2952-2957.

• Lulu Zheng, Sixiu Liu*, Guoshun Zhuang, Jian Xu, Qi Liu, Xinlian Zhang, Congrui Deng, Wang Zhao, Tingna Liu, Yiqi Wang, Yuxiao Zhang, Jin Lin, Qiongzhen Wang, Guodong Sui*, Signal Transductions of BEAS-2B Cells in Response to Carcinogenic PM2.5 Exposure Based on a Microfluidic System, Analytical Chemistry, 2017, 89(10), 5413–5421.

• Yuxiao Zhang﹟, Lulu Zheng﹟, Jiang Tuo, Qi Liu, Zhixuan Xu, Xinlian Zhang, Sixiu Liu*, Guodong Sui*, Analysis of PM2.5-induced cytotoxicity in human HaCaT cells based on a microfluidic system, Toxicology in Vitro, 2017,43, 1–8.